SYRE

SYRE Earnings Preview

Spyre Therapeutics, Inc. · Healthcare · $5B

13d until earnings

SYRE Earnings

Tuesday, May 05 2026
EPS Estimate
$-0.65
$-0.81 – $-0.53
Current Price
$71.27

Data Signal Summary

2 bullish
2 bearish
Insider selling cluster Put/call 0.1 (bullish skew) Analysts: bullish Price downtrend

Key Context

Analyst Consensus
bullish
Insider Activity
selling
Price Trend
downtrend
From 52w High
-2.9%
Est. Revisions (30d)
-0.8% 5up/3dn
Analyst Target (mean)
$88 $64–$115 +24%
Options P/C Ratio
0.14
Est. Dispersion
43% 12 analysts
Insider Cluster
strong sell
Fund Convergence
moderate D.E. Shaw, Citadel

Recent Activity

insider trades 17 transactions
Sell · TURTLE CAMERON (Chief Executive Officer) ·15,000 shares ·$739,912
Sell · BURROWS SCOTT L. (Chief Financial Officer) ·7,500 shares ·$370,076
Exercise · BURROWS SCOTT L. (Chief Financial Officer) ·7,500 shares ·$108,750
Sell · SLOAN SHELDON (Officer) ·7,958 shares ·$397,900
Exercise · SLOAN SHELDON (Officer) ·7,958 shares ·$172,370
12 more
Sell · BURROWS SCOTT L. ·2,500 shr ·$101,620
Exercise · BURROWS SCOTT L. ·2,500 shr ·$36,250
Sell · TURTLE CAMERON ·15,000 shr ·$632,866
Sell · TURTLE CAMERON ·15,000 shr ·$492,045
Sell · TURTLE CAMERON ·15,000 shr ·$460,134
Sell · TURTLE CAMERON ·15,000 shr ·$435,356
Sell · TURTLE CAMERON ·45,000 shr ·$1,049,778
Sell · BURROWS SCOTT L. ·18,428 shr ·$299,639
Sell · ALBERS JEFFREY W ·6,700 shr ·$246,313
Sell · ALBERS JEFFREY W ·300 shr ·$10,929
Sell · BURROWS SCOTT L. ·18,531 shr ·$522,074
Other · FAIRMOUNT FUNDS MANAGEMENT LLC ·3,639,680 shr
analyst ratings 9 ratings
Jones Trading Buy 4d ago
Wells Fargo Overweight 7d ago
Wedbush Outperform 7d ago
Baird Outperform 7d ago
Raymond James ·init Strong Buy 7d ago
4 more
Deutsche Bank Buy
Leerink Partners Outperform
Jefferies Buy
BTIG Buy