MDGL Earnings
Thursday, Apr 30 2026
EPS Estimate
$-4.14
$-4.48 – $-3.79
Revenue Estimate
$302M
Current Price
$532.02
Our Position
bullish · highFirst-in-class MASH drug Rezdiffra drives $958M launch year
structured data
est. revisions stable
Rezdiffra's launch validates a massive unmet need in MASH — a liver disease affecting millions with no prior approved therapy. The accelerating patient uptake and locked-in patent runway through 2045 position Madrigal to own this category for decades, with the German rollout signaling the start of a global revenue opportunity.
Watch: Track sequential patient growth and revenue per patient in Q1 2026 earnings to gauge whether the launch is sustaining momentum. International rollout cadence — particularly in major European markets — will signal how quickly Madrigal can scale beyond the US.
Data Signal Summary
0 bullish
3 bearish
Insider selling cluster
Put/call 1.5 (bearish skew)
Price downtrend
Key Context
Insider Activity
selling
Price Trend
downtrend
From 52w High
0.0%
Est. Revisions (30d)
+0.0% 0up/2dn
Analyst Target (mean)
$673 $529–$964 +26%
Options P/C Ratio
1.50
Est. Dispersion
17% 5 analysts
Insider Cluster
strong sell
Fund Convergence
strong D.E. Shaw, Citadel, Renaissance, Bridgewater
Recent Activity
insider trades
120 transactions
Sell
·
HUNTSMAN CAROLE A (Officer)
·419 shares
·$180,983
Sell
·
KELLEY SHANNON T (General Counsel)
·360 shares
·$155,498
Sell
·
TAUB REBECCA M.D. (Director)
·491 shares
·$212,083
Sell
·
SIBOLD WILLIAM JOHN (Chief Executive Officer)
·1,663 shares
·$718,316
Sell
·
DIER MARDI C (Chief Financial Officer)
·1,982 shares
·$853,993
115 more
Award
·
HUNTSMAN CAROLE A
·3,989 shr
Award
·
KELLEY SHANNON T
·4,017 shr
Award
·
SIBOLD WILLIAM JOHN
·14,995 shr
Award
·
DIER MARDI C
·5,215 shr
Award
·
SOERGEL DAVID M.D.
·4,374 shr
Sell
·
DIER MARDI C
·1,183 shr
·$505,389
Exercise
·
LEVY RICHARD S
·2,500 shr
·$18,400
Sell
·
HUNTSMAN CAROLE A
·910 shr
·$449,339
Sell
·
TAUB REBECCA M.D.
·647 shr
·$318,596
Exercise
·
LEVY RICHARD S
·4,000 shr
·$65,840
Sell
·
SIBOLD WILLIAM JOHN
·1,577 shr
·$776,546
Sell
·
KELLEY SHANNON T
·692 shr
·$344,173
Sell
·
TAUB REBECCA M.D.
·2,238 shr
·$1,098,343
Award
·
THAKKAR RITA
·2,398 shr
Sell
·
FRIEDMAN PAUL A
·24,520 shr
·$12,808,957
Exercise
·
FRIEDMAN PAUL A
·24,520 shr
·$387,416
Sell
·
FRIEDMAN PAUL A
·280 shr
·$154,348
Exercise
·
FRIEDMAN PAUL A
·280 shr
·$4,424
Sell
·
TAUB REBECCA M.D.
·18,410 shr
·$9,617,312
Exercise
·
TAUB REBECCA M.D.
·18,410 shr
·$290,878
Sell
·
TAUB REBECCA M.D.
·240 shr
·$132,080
Exercise
·
TAUB REBECCA M.D.
·240 shr
·$3,792
Sell
·
FRIEDMAN PAUL A
·24,800 shr
·$13,694,158
Exercise
·
FRIEDMAN PAUL A
·24,800 shr
·$391,840
Other
·
TAUB REBECCA M.D.
·5,455 shr
Sell
·
TAUB REBECCA M.D.
·18,650 shr
·$10,297,573
Exercise
·
TAUB REBECCA M.D.
·18,650 shr
·$294,670
Sell
·
SIBOLD WILLIAM JOHN
·2,400 shr
·$1,380,816
Other
·
SIBOLD WILLIAM JOHN
·50,000 shr
Sell
·
DIER MARDI C
·4,173 shr
·$2,413,416
Exercise
·
DIER MARDI C
·4,173 shr
·$1,050,052
Sell
·
HUNTSMAN CAROLE A
·1,958 shr
·$1,082,986
Sell
·
LEVY RICHARD S
·8,500 shr
·$4,428,198
Exercise
·
LEVY RICHARD S
·8,500 shr
·$117,160
Sell
·
BATE KENNETH M
·16,575 shr
·$8,027,354
Exercise
·
BATE KENNETH M
·16,575 shr
·$3,399,036
Sell
·
SIBOLD WILLIAM JOHN
·7,279 shr
·$3,243,741
Sell
·
SIBOLD WILLIAM JOHN
·7,616 shr
·$3,047,756
Buy
·
BAKER BROS ADVISORS, L.P.
·97,065 shr
·$36,941,197
Sell
·
KELLEY SHANNON T
·1,304 shr
·$479,627
Buy
·
BAKER BROS ADVISORS, L.P.
·68,618 shr
·$24,979,827
Sell
·
BATE KENNETH M
·10,000 shr
·$3,652,009
Sell
·
WALTERMIRE ROBERT E.
·442 shr
·$120,847
Exercise
·
BATE KENNETH M
·10,000 shr
·$164,600
Sell
·
FRIEDMAN PAUL A
·129,172 shr
·$47,825,149
Exercise
·
FRIEDMAN PAUL A
·129,172 shr
·$1,220,675
Sell
·
FRIEDMAN PAUL A
·46,808 shr
·$16,631,386
Exercise
·
FRIEDMAN PAUL A
·46,808 shr
·$442,336
Sell
·
TAUB REBECCA M.D.
·46,463 shr
·$16,509,032
Exercise
·
TAUB REBECCA M.D.
·46,463 shr
·$439,075
Award
·
BRENNAN DANIEL J
·967 shr
Sell
·
FRIEDMAN PAUL A
·1,400 shr
·$490,044
Exercise
·
FRIEDMAN PAUL A
·1,400 shr
·$13,230
Sell
·
TAUB REBECCA M.D.
·1,000 shr
·$350,005
Exercise
·
TAUB REBECCA M.D.
·1,000 shr
·$9,450
Sell
·
FRIEDMAN PAUL A
·28,876 shr
·$10,198,844
Exercise
·
FRIEDMAN PAUL A
·28,876 shr
·$272,878
Sell
·
TAUB REBECCA M.D.
·29,101 shr
·$10,278,098
Exercise
·
TAUB REBECCA M.D.
·29,101 shr
·$275,004
Award
·
FRIEDMAN PAUL A
·715 shr
Award
·
BATE KENNETH M
·715 shr
Award
·
FOUSE JACQUALYN A.
·203 shr
Award
·
LEVY RICHARD S
·715 shr
Award
·
DALY JAMES M.
·715 shr
Award
·
BAKER BROS ADVISORS, L.P.
·2,860 shr
Award
·
SOERGEL DAVID M.D.
·7,545 shr
Sell
·
CRAVES FREDERICK B
·15,470 shr
·$5,082,480
Exercise
·
CRAVES FREDERICK B
·15,470 shr
·$1,282,478
Award
·
FOUSE JACQUALYN A.
·894 shr
Sell
·
DIER MARDI C
·258 shr
·$83,344
Award
·
WALTERMIRE ROBERT E.
·2,061 shr
Sell
·
WALTERMIRE ROBERT E.
·14,113 shr
·$4,817,104
Exercise
·
WALTERMIRE ROBERT E.
·14,113 shr
·$1,234,766
Award
·
HUNTSMAN CAROLE A
·3,386 shr
Award
·
KELLEY SHANNON T
·3,187 shr
Award
·
TAUB REBECCA M.D.
·4,382 shr
Award
·
SIBOLD WILLIAM JOHN
·13,066 shr
Award
·
DIER MARDI C
·3,784 shr
Sell
·
HUNTSMAN CAROLE A
·1,834 shr
·$597,840
Sell
·
KELLEY SHANNON T
·415 shr
·$139,025
Sell
·
DIER MARDI C
·1,961 shr
·$637,248
Sell
·
WALTERMIRE ROBERT E.
·1,227 shr
·$418,488
Sell
·
BATE KENNETH M
·20,000 shr
·$7,128,759
Exercise
·
BATE KENNETH M
·20,000 shr
·$1,325,287
Sell
·
DALY JAMES M.
·15,470 shr
·$5,375,126
Exercise
·
DALY JAMES M.
·15,470 shr
·$1,282,478
Sell
·
WALTERMIRE ROBERT E.
·103 shr
·$34,530
Sell
·
HUNTSMAN CAROLE A
·347 shr
·$116,328
Sell
·
TAUB REBECCA M.D.
·648 shr
·$217,236
Sell
·
SIBOLD WILLIAM JOHN
·1,584 shr
·$531,020
Sell
·
KELLEY SHANNON T
·277 shr
·$75,735
Sell
·
TAUB REBECCA M.D.
·1,689 shr
·$461,789
Sell
·
CRAVES FREDERICK B
·3,600 shr
·$1,135,122
Sell
·
CRAVES FREDERICK B
·3,400 shr
·$1,191,028
Sell
·
HUNTSMAN CAROLE A
·688 shr
·$218,041
Sell
·
LEVY RICHARD S
·5,000 shr
·$1,750,000
Exercise
·
LEVY RICHARD S
·5,000 shr
·$36,800
Sell
·
LEVY RICHARD S
·5,000 shr
·$1,504,703
Other
·
CRAVES FREDERICK B
·15,000 shr
Sell
·
SIBOLD WILLIAM JOHN
·6,363 shr
·$1,551,490
Award
·
KELLEY SHANNON T
·5,215 shr
Award
·
CRAVES FREDERICK B
·714 shr
Award
·
FRIEDMAN PAUL A
·714 shr
Award
·
BATE KENNETH M
·714 shr
Award
·
LEVY RICHARD S
·714 shr
Award
·
DALY JAMES M.
·714 shr
Award
·
BAKER BROS ADVISORS, L.P.
·2,856 shr
Sell
·
WALTERMIRE ROBERT E.
·1,900 shr
·$532,000
Exercise
·
WALTERMIRE ROBERT E.
·1,900 shr
·$165,471
Sell
·
WALTERMIRE ROBERT E.
·2,000 shr
·$570,000
Exercise
·
WALTERMIRE ROBERT E.
·2,000 shr
·$175,840
Other
·
CRAVES FREDERICK B
·84,852 shr
Sell
·
WALTERMIRE ROBERT E.
·1,036 shr
·$239,668
Sell
·
CRAVES FREDERICK B
·22,489 shr
·$4,787,404
Exercise
·
CRAVES FREDERICK B
·22,489 shr
·$2,316,844
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