KRYS Earnings
Monday, May 04 2026
EPS Estimate
$1.39
$1.28 – $1.69
Revenue Estimate
$112M
Current Price
$274.21
Our Position
bullishGuggenheim raises PT 27% on strong VYJUVEK ramp
structured data
est. revisions rising
(+22.7pp / 30d)
VYJUVEK's $389M annual revenue run-rate validates commercial execution in a first-mover rare disease gene therapy market. The 27% price target raise paired with sustained Buy conviction signals Guggenheim sees clear visibility to sustained growth as international expansion accelerates and reimbursement penetration deepens in the U.S. — this is a pathway to durable, profitable growth in one of biotech's most capital-efficient franchises.
Watch: Track Q1 2026 patient additions and Italy launch timing in the spring/summer. Both data points directly answer whether international revenue can replicate U.S. traction or if VYJUVEK adoption plateaus outside the U.S. market.
Data Signal Summary
2 bullish
2 bearish
Estimates up +4%
Insider selling cluster
Put/call 0.5 (bullish skew)
Price downtrend
Key Context
Insider Activity
selling
Price Trend
downtrend
From 52w High
0.0%
P/E Ratio
39.1
Est. Revisions (30d)
+4.0% 0up/0dn
Analyst Target (mean)
$314 $241–$371 +15%
Options P/C Ratio
0.51
Est. Dispersion
28% 7 analysts
Insider Cluster
strong sell
Fund Convergence
strong Citadel, D.E. Shaw, Bridgewater, Renaissance
Recent Activity
insider trades
37 transactions
Sell
·
KRISHNAN SUMA M (Officer, Director and Beneficial Owner)
·25,000 shares
·$6,580,270
Sell
·
KRISHNAN KRISH S (Chief Executive Officer)
·25,000 shares
·$6,579,164
Sell
·
ROMANO KATHRYN (Officer)
·750 shares
·$200,700
Sell
·
JANNEY DANIEL SPENCER (Director)
·11,803 shares
·$3,252,824
Other
·
KRISHNAN SUMA M (Officer, Director and Beneficial Owner)
·67,225 shares
32 more
Other
·
KRISHNAN KRISH S
·67,225 shr
Other
·
ROMANO KATHRYN
·8,050 shr
Sell
·
JANNEY DANIEL SPENCER
·60,161 shr
·$16,149,383
Exercise
·
JANNEY DANIEL SPENCER
·37,895 shr
·$93,222
Sell
·
ROSSI DINO A
·18,950 shr
·$4,953,694
Exercise
·
ROSSI DINO A
·18,950 shr
·$166,570
Other
·
ROMANO KATHRYN
·750 shr
Sell
·
ROMANO KATHRYN
·12,500 shr
·$3,401,705
Exercise
·
ROMANO KATHRYN
·12,500 shr
·$794,375
Other
·
KRISHNAN SUMA M
·5,000 shr
Other
·
KRISHNAN KRISH S
·5,000 shr
Sell
·
KRISHNAN SUMA M
·50,000 shr
·$11,007,333
Sell
·
KRISHNAN KRISH S
·50,000 shr
·$11,007,447
Sell
·
KRISHNAN SUMA M
·35,873 shr
·$5,395,001
Sell
·
KRISHNAN KRISH S
·35,873 shr
·$5,395,001
Sell
·
KRISHNAN SUMA M
·14,127 shr
·$2,122,835
Sell
·
KRISHNAN KRISH S
·14,127 shr
·$2,122,835
Sell
·
KRISHNAN SUMA M
·50,000 shr
·$8,889,525
Sell
·
KRISHNAN KRISH S
·50,000 shr
·$8,889,525
Other
·
KRISHNAN SUMA M
·77,500 shr
Other
·
KRISHNAN KRISH S
·77,500 shr
Other
·
ROMANO KATHRYN
·12,500 shr
Sell
·
ROMANO KATHRYN
·750 shr
·$131,415
Sell
·
KRISHNAN SUMA M
·50,000 shr
·$8,240,023
Sell
·
KRISHNAN KRISH S
·50,000 shr
·$8,240,023
Other
·
ROSSI DINO A
·5,000 shr
Sell
·
KRISHNAN SUMA M
·50,000 shr
·$9,888,276
Sell
·
KRISHNAN KRISH S
·50,000 shr
·$9,888,276
Sell
·
KRISHNAN SUMA M
·50,000 shr
·$8,788,062
Sell
·
KRISHNAN KRISH S
·50,000 shr
·$8,788,062
Sell
·
GANGOLLI JULIAN S.
·20,000 shr
·$3,282,690
Exercise
·
GANGOLLI JULIAN S.
·20,000 shr
·$455,000
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