TSHA Taysha Gene Therapies, Inc.

bullish · high conviction track record →
Get emailed when TSHA changes direction
Mkt Cap $2B 52wk $1.70 - $6.76 3h ago
Insider selling: $6,373,997 sold by 8 insiders (30d)
Est. revisions: +2.0% (1 up, 0 down in 30d)
Backed by structured data (insider trades, analyst ratings, or filings)
Factor Model (net +1.7)

Factor Model

net +1.7
Est. Revisions
+0.1
Insider Activity
+0.0
Momentum
+0.0
Analyst Rev.
+1.0
Narrative Gap
+0.0

TSHA insiders buy as stock rallies 343%

Watch: Upcoming quarterly earnings and clinical trial updates could drive the next significant price move given current momentum and analyst focus.

TSHA stock soared 343% year-over-year and gained 22.5% YTD, supported by insider Paul B. Manning buying $5.06M worth of shares near $2.25-$2.75. Analysts Needham and Canaccord reiterated buys with price targets of $12 and $17 respectively. Despite bullish insider buying, overall insider activity shows net selling amid decelerating revenue momentum and high short interest.

Insider buys and price target upgrades signal growing confidence despite mixed insider sentiment and fundamental challenges, suggesting potential for further gains in this volatile biotech.

Evidence

Updated Friday Insider buy by MANNING PAUL B. (TSHA): $2,062,500
Updated Friday Insider buy by MANNING PAUL B. (TSHA): $2,999,999
Fundamentals & Data ▾
Taysha Gene Therapies, Inc. Healthcare · Biotechnology
Mkt Cap
$2B
Beta
1.08
52w Range
$1.70 - $6.76
Short Interest
42.3M 16.35%
Days to Cover
13.5 -15%
Insiders
selling 2B / 5S
EPS Estimate
$-0.10 +2.0% 30d 1up / 0dn
Est. Dispersion
51% 5 analysts
Analyst Target
$12 $7 - $19
Options P/C
2.98
Insider Cluster
strong sell 1B / 3S
Fund Convergence
strong Citadel, D.E. Shaw, Renaissance, Two Sigma
Financials
Revenue
$5M +171% YoY
FCF
$-27M
Op Margin
-516%
Momentum: decelerating
Top Holders
Citadel $11M
D.E. Shaw $4M
Renaissance
Two Sigma
Recent Filings & Data
insider trade 30
net selling · $6,373,997 sold · $5,062,499 bought
8 insiders · 30 transactions (30d)
Recent transactions
NAGENDRAN SUKUMAR · sell · $892,000
NAGENDRAN SUKUMAR · exercise · $32,526
ALAM KAMRAN · sell · $7,481
NOLAN SEAN PATRICK · sell · $840,196
NAGENDRAN SUKUMAR · sell · $547,469
ALAM KAMRAN · sell · $485,042
NOLAN SEAN PATRICK · award
NAGENDRAN SUKUMAR · award
NAGENDRAN SUKUMAR · sell · $942,000
NAGENDRAN SUKUMAR · exercise · $229,440
ALAM KAMRAN · award
NAGENDRAN SUKUMAR · sell · $1,695,906
NAGENDRAN SUKUMAR · exercise · $562,043
NAGENDRAN SUKUMAR · sell · $646,000
NAGENDRAN SUKUMAR · exercise · $28,760
NAGENDRAN SUKUMAR · sell · $162,604
ALAM KAMRAN · sell · $155,299
DONENBERG PHILLIP BRIAN · award
STALFORT JOHN A · award
SEPP-LORENZINO LAURA · award
LONG ALISON S · award
MANNING PAUL B. · buy · $2,062,500
NOLAN SEAN PATRICK · award
NAGENDRAN SUKUMAR · award
ALAM KAMRAN · award
MANNING PAUL B. · buy · $2,999,999
DONENBERG PHILLIP BRIAN · award
STALFORT JOHN A · award
SEPP-LORENZINO LAURA · award
LONG ALISON S · award
3 signals · latest Updated Friday

Get alerted when TSHA changes direction

We'll email you when our AI detects a shift — reversals, insider clusters, filing red flags.