Get emailed when KYMR changes direction
Mkt Cap $7B
52wk $28.06 - $103.00
3h ago
Insider buying: $215,297,312 bought by 13 insiders (30d)
Factor divergence:
DIVERGENCE: insider_activity, analyst_revisions bullish vs options_sentiment bearish
Est. revisions:
+0.0%
(6 up, 4 down in 30d)
Backed by structured data (insider trades, analyst ratings, or filings)
Factor Model (net +0.7)
Factor Model
net +0.7
Est. Revisions
+0.0
Insider Activity
+0.5
Momentum
+0.0
Analyst Rev.
+0.4
Narrative Gap
+0.0
KYMR wins FDA fast track, insiders buy $215M
Watch: Next catalyst is KT-621 Phase 2b trial data, critical for regulatory progress and valuation upside.
KYMR received FDA Fast Track for KT-621 targeting eosinophilic asthma in Phase 2b trials, accelerating approval prospects. Gilead Sciences exercised an option on KT-200, paying $45M in milestones and aiming for IND filing in 2027. Insiders led by Baker Bros and BVF Partners bought $215M of shares at $44-$86, signaling strong confidence amid mixed analyst EPS revisions and a 61% revenue drop last year.
Fast Track status and Gilead's milestone payment validate KYMR's pipeline potential despite steep revenue declines, driving high insider conviction and institutional interest.
Evidence
Updated Friday
Insider buy by BAKER BROS ADVISORS L.P. (KYMR): $46
Updated Friday
Insider buy by BAKER BROS ADVISORS L.P. (KYMR): $28,842,000
Updated Friday
Insider buy by BVF PARTNERS L P (KYMR): $13,955,348
Updated Friday
Insider buy by BAKER BROS ADVISORS L.P. (KYMR): $172,499,918
Updated Friday
FDA Grants Fast Track Designation to Kymera Therapeutics, Inc. (KYMR)’s KT-621 for Eosinophilic Asthma
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Fundamentals & Data ▾
Kymera Therapeutics, Inc.
Healthcare · Biotechnology
Mkt Cap
$7B
Beta
2.29
52w Range
$28.06 - $103.00
Short Interest
10.4M 15.28%
Days to Cover
14.5 +1%
Technicals
downtrend
from 52w Hi
-4.3%
1w return
-3.2%
Insiders
selling
0B / 9S
EPS Estimate
$-0.86
+0.0% 30d
6up / 4dn
Est. Dispersion
53%
19 analysts
Analyst Target
$119
$91 - $140
Options P/C
2.58
Insider Cluster
buy cluster
2B / 7S
Fund Convergence
strong
D.E. Shaw, Two Sigma, Citadel
Financials
Revenue
$3M -61% YoY
FCF
$-67M
Op Margin
-3411%
Momentum:
accelerating
Top Holders
D.E. Shaw
$343M
Two Sigma
$29M
Citadel
$14M
Recent Filings & Data
insider trade
88
net buying
· $53,271,114 sold
· $215,297,312 bought
13 insiders · 88 transactions (30d)
Recent transactions
CHADWICK JEREMY G · sell · $589,598
CHADWICK JEREMY G · exercise · $225,437
GOODMAN NOAH · sell · $121,230
GOODMAN NOAH · sell · $897,782
GOODMAN NOAH · exercise · $52,625
CHADWICK JEREMY G · sell · $1,900,048
CHADWICK JEREMY G · exercise · $659,194
RIDLOFF ELENA · sell · $1,024,660
RIDLOFF ELENA · exercise · $170,160
CHADWICK JEREMY G · sell · $9,048,290
CHADWICK JEREMY G · exercise · $3,234,524
ESPOSITO PAMELA · sell · $197,877
ESPOSITO PAMELA · exercise · $122,750
CHADWICK JEREMY G · sell · $2,145,673
CHADWICK JEREMY G · exercise · $870,000
CHADWICK JEREMY G · sell · $515,594
GOLLOB JARED AUGUST · sell · $916,669
JACOBS BRUCE N. · sell · $1,091,231
CHADWICK JEREMY G · award
ADAMS BRIAN R · award
GOLLOB JARED AUGUST · award
JACOBS BRUCE N. · award
GOODMAN NOAH · award
MAINOLFI NELLO · sell · $2,707,813
MAINOLFI NELLO · exercise · $62,400
ESPOSITO PAMELA · sell · $218,270
ESPOSITO PAMELA · sell · $373,521
ESPOSITO PAMELA · exercise · $216,350
MAINOLFI NELLO · exercise · $99,994
MAINOLFI NELLO · sell · $2,341,939
ESPOSITO PAMELA · sell · $2,264,480
ESPOSITO PAMELA · exercise · $1,042,483
MAINOLFI NELLO · exercise · $99,985
BAKER BROS ADVISORS L.P. · buy · $172,499,918
ALBERS JEFFREY W · sell · $333,100
ALBERS JEFFREY W · exercise · $70,900
GOLLOB JARED AUGUST · sell · $3,284,832
GOLLOB JARED AUGUST · exercise · $262,806
MAINOLFI NELLO · sell · $6,662,000
MAINOLFI NELLO · exercise · $208,000
MAINOLFI NELLO · sell · $1,829,737
GOLLOB JARED AUGUST · sell · $3,659,254
GOLLOB JARED AUGUST · exercise · $84,185
ALBERS JEFFREY W · sell · $295,949
ALBERS JEFFREY W · exercise · $51,700
GOLLOB JARED AUGUST · sell · $186,840
GOLLOB JARED AUGUST · exercise · $2,448
JACOBS BRUCE N. · sell · $3,961,380
JACOBS BRUCE N. · exercise · $164,778
MAINOLFI NELLO · sell · $1,470,000
ADAMS BRIAN R · award
BVF PARTNERS L P · buy · $13,955,348
BAKER BROS ADVISORS L.P. · buy · $28,842,000
RIDLOFF ELENA · sell · $225,000
RIDLOFF ELENA · exercise · $91,305
ALBERS JEFFREY W · sell · $311,101
ALBERS JEFFREY W · exercise · $65,649
ESPOSITO PAMELA · sell · $245,186
ESPOSITO PAMELA · exercise · $147,750
RIDLOFF ELENA · sell · $553,200
RIDLOFF ELENA · exercise · $332,040
CHADWICK JEREMY G · sell · $75,436
GOODMAN NOAH · award
JACOBS BRUCE N. · exercise · $52,000
CHADWICK JEREMY G · award
CHADWICK JEREMY G · sell · $42,113
CHINIARA ELLEN V · award
CHINIARA ELLEN V · sell · $68,239
GOLLOB JARED AUGUST · award
GOLLOB JARED AUGUST · sell · $174,786
JACOBS BRUCE N. · award
JACOBS BRUCE N. · sell · $214,219
JACOBS BRUCE N. · exercise · $20,800
MAINOLFI NELLO · exercise · $20,800
CHINIARA ELLEN V · sell · $130,645
ESPOSITO PAMELA · sell · $122,500
ESPOSITO PAMELA · exercise · $73,875
ESPOSITO PAMELA · sell · $651,766
ESPOSITO PAMELA · exercise · $322,075
ALBERS JEFFREY W · sell · $245,508
BAKER BROS ADVISORS L.P. · buy · $46
GOLLOB JARED AUGUST · sell · $1,803,143
GOLLOB JARED AUGUST · exercise · $82,368
MAINOLFI NELLO · exercise · $100,060
MAINOLFI NELLO · exercise · $29,979
HOROBIN JOANNA C · sell · $280,400
HOROBIN JOANNA C · exercise · $17,680
CHADWICK JEREMY G · sell · $90,105
6 signals · latest Updated Friday
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