TYRA

TYRA Earnings Preview

Tyra Biosciences, Inc. · Healthcare · $2B

8d until earnings

TYRA Earnings

Thursday, May 07 2026
EPS Estimate
$-0.59
$-0.64 – $-0.56
Current Price
$35.06

Our Position

bullish · high

RA Capital buys $35M TYRA shares; Guggenheim starts Buy

structured data est. revisions stable

Aggressive insider buying and a new high target reflect growing confidence in TYRA's lead drug and pipeline, despite recent modest insider selling and EPS estimate revisions.

Watch: Monitor TYRA's upcoming clinical trial data for dabogratinib to validate growth prospects and confirm Guggenheim's bullish thesis.

Data Signal Summary

2 bullish
0 bearish
Insider buying cluster Put/call 0.1 (bullish skew)

Key Context

Insider Activity
selling
Price Trend
mixed
1-Month Return
+2.4%
From 52w High
-5.1%
Est. Revisions (30d)
-0.1% 1up/4dn
Analyst Target (mean)
$51 $37–$60 +46%
Options P/C Ratio
0.11
Est. Dispersion
14% 10 analysts
Insider Cluster
strong buy (officer)
Fund Convergence
strong D.E. Shaw, Two Sigma, Citadel

Recent Activity

insider trades 37 transactions
Exercise · KAPLAN GILLA (Director) ·67,467 shares ·$151,801
Sell · KAPLAN GILLA (Director) ·14,295 shares ·$528,506
Award · HARRIS TODD JAMES (Chief Executive Officer) ·1,463 shares ·$52,990
Award · FUHRMAN ALAN CPA (Chief Financial Officer) ·1,376 shares ·$49,839
Sell · BENSEN DANIEL (Officer) ·8,000 shares ·$262,965
32 more
Sell · BENSEN DANIEL ·8,000 shr ·$228,186
Sell · MORE ROBERT J ·10,000 shr ·$250,000
Sell · BENSEN DANIEL ·8,000 shr ·$181,159
Sell · MORE ROBERT J ·246,871 shr ·$5,000,026
Sell · BENSEN DANIEL ·125,589 shr ·$2,030,923
Sell · BENSEN DANIEL ·131,411 shr ·$2,108,067
Award · FUHRMAN ALAN CPA ·701 shr ·$8,629
Sell · KAPLAN GILLA ·9,578 shr ·$93,700
Sell · KAPLAN GILLA ·51,814 shr ·$534,563
Buy · RA CAPITAL MANAGEMENT, L.P. ·163,287 shr ·$1,664,700
Buy · RA CAPITAL MANAGEMENT, L.P. ·186,850 shr ·$1,904,002
Buy · RA CAPITAL MANAGEMENT, L.P. ·1,211,198 shr ·$11,751,304
Award · HARRIS TODD JAMES ·1,241 shr ·$12,131
Award · FUHRMAN ALAN CPA ·1,238 shr ·$12,101
Sell · KJELLSON NINA S ·5,401 shr ·$74,324
Sell · KJELLSON NINA S ·4,825 shr ·$78,466
Sell · KJELLSON NINA S ·25,041 shr ·$409,645
Sell · KJELLSON NINA S ·5,272 shr ·$88,773
Buy · RA CAPITAL MANAGEMENT, L.P. ·1,220,681 shr ·$19,836,066
Sell · KJELLSON NINA S ·74,582 shr ·$1,284,133
Sell · KJELLSON NINA S ·11,569 shr ·$194,248
Sell · KJELLSON NINA S ·138,711 shr ·$2,282,656
Buy · FUHRMAN ALAN CPA ·9,500 shr ·$151,954
Sell · HARRIS TODD JAMES ·62,720 shr ·$1,711,247
Sell · HARRIS TODD JAMES ·58,726 shr ·$1,513,271
Sell · HARRIS TODD JAMES ·500 shr ·$12,000
Sell · HARRIS TODD JAMES ·11,747 shr ·$283,223
Sell · HARRIS TODD JAMES ·16,307 shr ·$394,441
Award · HARRIS TODD JAMES ·1,350 shr ·$28,674
Award · FUHRMAN ALAN CPA ·954 shr ·$20,263
Exercise · KAPLAN GILLA ·61,392 shr ·$37,449
Sell · BENSEN DANIEL ·3,702 shr ·$74,045