NGNE

NGNE Earnings Preview

Neurogene Inc. · Healthcare · $433M

14d until earnings

NGNE Earnings

Thursday, May 07 2026
EPS Estimate
$-1.28
$-1.68 – $-1.00
Current Price
$26.50

Our Position

bullish · high

FDA Breakthrough Designation Triggers 25% Jump

structured data est. revisions rising (+12.8pp / 30d)

This is a de-risking event for a biotech at an inflection point. Breakthrough designation is not given lightly—it signals the FDA believes this therapy addresses unmet medical need with credible mechanism. Combined with interim Phase 1/2 proof-of-concept, the Embolden pivotal trial has structural momentum. For a $200M market-cap stock, a validated gene therapy in a neurology orphan indication is exponentially more valuable than a mid-stage asset.

Watch: Q2 2026 dosing completion and mid-2026 interim data release. These will confirm safety and efficacy in the pivotal trial—the real moment investors are pricing in.

Data Signal Summary

2 bullish
1 bearish
Insider buying cluster Put/call 0.0 (bullish skew) Price downtrend

Key Context

Insider Activity
selling
Price Trend
downtrend
From 52w High
-4.8%
Est. Revisions (30d)
-0.6% 3up/1dn
Analyst Target (mean)
$78 $46–$180 +193%
Options P/C Ratio
0.01
Est. Dispersion
53% 5 analysts
Insider Cluster
strong buy (officer)
Fund Convergence
moderate Citadel, Renaissance

Recent Activity

insider trades 19 transactions
Sell · JORDAN JULIE (Officer) ·828 shares ·$18,128
Sell · CVIJIC CHRISTINE MIKAIL (President) ·2,558 shares ·$55,316
Sell · MCMINN RACHEL L. PH.D. (Chief Executive Officer) ·3,352 shares ·$73,995
Sell · COBB STUART (Officer) ·6,797 shares ·$141,446
Sell · CVIJIC CHRISTINE MIKAIL (President) ·4,045 shares ·$84,176
14 more
Sell · CVIJIC CHRISTINE MIKAIL ·4,800 shr ·$120,526
Award · JORDAN JULIE ·4,900 shr
Award · COBB STUART ·16,500 shr
Award · CVIJIC CHRISTINE MIKAIL ·22,000 shr
Award · MCMINN RACHEL L. PH.D. ·25,900 shr
Sell · COBB STUART ·6,797 shr ·$103,003
Award · JORDAN JULIE ·8,400 shr
Award · COBB STUART ·7,200 shr
Award · CVIJIC CHRISTINE MIKAIL ·20,300 shr
Award · MCMINN RACHEL L. PH.D. ·23,900 shr
Sell · CVIJIC CHRISTINE MIKAIL ·4,501 shr ·$76,247
Buy · SAMSARA BIOCAPITAL GP, LLC ·48,770 shr ·$1,259,623
Buy · CVIJIC CHRISTINE MIKAIL ·24,000 shr ·$491,400
Buy · MCMINN RACHEL L. PH.D. ·47,500 shr ·$969,000