LXRX

LXRX Earnings Preview

Lexicon Pharmaceuticals, Inc. · Healthcare · $780M

18d until earnings

LXRX Earnings

Tuesday, May 12 2026
EPS Estimate
$-0.04
$-0.06 – $-0.02
Revenue Estimate
$10M
Current Price
$1.82

Our Position

bullish · high

Pilavapadin 10mg Cuts DPNP Pain in Phase 2b

est. revisions falling (-46.2pp / 30d)

Positive Phase 2b results support pilavapadin's potential as a treatment in a challenging market, enhancing Lexicon's clinical pipeline and near-term visibility.

Watch: Watch the April 22 presentation for detailed efficacy and safety data to gauge commercial viability and investor reaction.

Data Signal Summary

2 bullish
1 bearish
Insider buying cluster Put/call 0.1 (bullish skew) Price downtrend

Key Context

Insider Activity
buying
Price Trend
downtrend
From 52w High
-2.7%
Est. Revisions (30d)
+0.0% 0up/0dn
Analyst Target (mean)
$3 $1–$6 +85%
Options P/C Ratio
0.05
Est. Dispersion
114% 4 analysts
Insider Cluster
buy cluster
Fund Convergence
strong Citadel, Renaissance, Two Sigma

Recent Activity

insider trades 33 transactions
Other · COIANTE SCOTT M (Chief Financial Officer) ·160,237 shares
Other · CRUM BRIAN T (General Counsel) ·273,006 shares
Other · DEFRANCESCO LISA (Officer) ·152,864 shares
Other · GRANOWITZ CRAIG B. M.D., PH.D. (Officer) ·312,276 shares
Other · MCDERMOTT WENDY (Officer) ·224,406 shares
28 more
Other · EXTON MICHAEL ·503,263 shr
Other · MARTENS RACHEL YAP ·67,090 shr
Other · GOPINATHAN SUMA ·99,950 shr
Buy · DEBBANE RAYMOND ·2,000 shr ·$2,980
Buy · DEBBANE RAYMOND ·100,000 shr ·$147,000
Buy · DEBBANE RAYMOND ·150,000 shr ·$219,755
Buy · DEBBANE RAYMOND ·268,497 shr ·$352,889
Award · INVUS GLOBAL MANAGEMENT, LLC ·22,400,000 shr ·$29,120,000
Buy · INVUS GLOBAL MANAGEMENT, LLC ·1,538,462 shr ·$2,000,001
Other · SOBECKI CHRISTOPHER J ·36,810 shr
Other · DEBBANE RAYMOND ·36,810 shr
Other · SWAIN JUDITH L ·36,810 shr
Other · BARKER SAMUEL L ·36,810 shr
Other · AMOUYAL PHILIPPE ·36,810 shr
Other · SULLIVAN DIANE E ·36,810 shr
Other · CRUM BRIAN T ·128,940 shr
Other · DEFRANCESCO LISA ·24,673 shr
Other · GRANOWITZ CRAIG B. M.D., PH.D. ·137,934 shr
Other · ALEXANDER KRISTEN ·46,430 shr
Other · MAIN ALAN J ·126,814 shr
Other · MCDERMOTT WENDY ·98,956 shr
Other · ARTAL INTERNATIONAL S.C.A. ·57,546,100 shr
Other · SOBECKI CHRISTOPHER J ·8,032 shr
Other · LEFKOWITZ ROBERT J ·8,032 shr
Other · DEBBANE RAYMOND ·8,032 shr
Other · SWAIN JUDITH L ·8,032 shr
Other · BARKER SAMUEL L ·8,032 shr
Other · AMOUYAL PHILIPPE ·8,032 shr