IMNM

IMNM Earnings Preview

Immunome, Inc. · Healthcare · $3B

14d until earnings

IMNM Earnings

Tuesday, May 12 2026
EPS Estimate
$-0.54
$-0.66 – $-0.46
Revenue Estimate
$0M
Current Price
$23.56

Our Position

bullish

Redmile Doubles Down on Clinical Biotech Upswing

structured data est. revisions falling (-3.0pp / 30d)

Redmile's concentrated bet — now its 9th largest position — suggests the fund believes Immunome's Phase 3 data is durable enough to justify a 9% weighting in a diversified biotech portfolio. The positioning matters: an 18-month rally followed by institutional capital backing doesn't guarantee approval (regulatory risk remains), but it signals the market is pricing a meaningful probability of success.

Watch: The path to varegacestat approval — Immunome will need to file and navigate FDA review, likely 12-18 months out. Watch also for any Phase 3 data readouts from the rest of the pipeline and whether the $400 million burn rate sustains clinical progress without another dilutive raise.

Data Signal Summary

1 bullish
2 bearish
Insider buying cluster Put/call 3.0 (bearish skew) Price downtrend

Key Context

Insider Activity
buying
Price Trend
downtrend
From 52w High
-4.3%
Est. Revisions (30d)
+0.0% 5up/1dn
Analyst Target (mean)
$36 $30–$40 +51%
Options P/C Ratio
2.97
Est. Dispersion
37% 12 analysts
Insider Cluster
strong buy (officer)
Fund Convergence
moderate Citadel, D.E. Shaw

Recent Activity

insider trades 33 transactions
Sell · ROSETT MAX (Chief Financial Officer) ·65,000 shares ·$1,424,916
Exercise · ROSETT MAX (Chief Financial Officer) ·71,561 shares ·$87,053
Sell · HIGGINS JACK (Officer) ·9,438 shares ·$204,238
Other · HIGGINS JACK (Officer) ·6,291 shares
Buy · SIEGALL CLAY B (Chief Executive Officer) ·25,450 shares ·$500,602
28 more
Sell · WAGENHEIM PHILIP R ·65,000 shr ·$1,335,626
Buy · BIENAIME JEAN-JACQUES ·2,000 shr ·$43,670
Buy · SIEGALL CLAY B ·4,729 shr ·$100,018
Sell · BARCHAS ISAAC ·383,200 shr ·$8,330,080
Buy · SIEGALL CLAY B ·7,278 shr ·$149,053
Other · SIEGALL CLAY B ·200,000 shr
Other · HIGGINS JACK ·3,000 shr
Buy · TSAI PHILIP S. L. ·10,000 shr ·$204,900
Buy · SIEGALL CLAY B ·46,511 shr ·$999,986
Exercise · HIGGINS JACK ·22,000 shr ·$29,700
Buy · BIENAIME JEAN-JACQUES ·5,000 shr ·$46,900
Exercise · HIGGINS JACK ·5,200 shr ·$7,020
Buy · SIEGALL CLAY B ·137,100 shr ·$999,459
Buy · BIENAIME JEAN-JACQUES ·7,800 shr ·$60,684
Buy · BIENAIME JEAN-JACQUES ·7,000 shr ·$57,470
Buy · TSAI PHILIP S. L. ·12,300 shr ·$103,566
Buy · SIEGALL CLAY B ·150,000 shr ·$1,654,500
Buy · SIEGALL CLAY B ·100,000 shr ·$962,181
Buy · LECHLEIDER ROBERT M.D. ·15,805 shr ·$149,800
Buy · TSAI PHILIP S. L. ·21,000 shr ·$198,030
Sell · ROSETT MAX ·14,380 shr ·$230,224
Exercise · ROSETT MAX ·42,000 shr ·$44,100
Other · HIGGINS JACK ·2,471 shr
Buy · BIENAIME JEAN-JACQUES ·7,000 shr ·$97,608
Sell · HIGGINS JACK ·3,524 shr ·$49,072
Exercise · HIGGINS JACK ·19,524 shr ·$26,357
Buy · BIENAIME JEAN-JACQUES ·2,000 shr ·$27,140
Buy · SIEGALL CLAY B ·100,000 shr ·$1,388,072